Anticlastogenic Effect of Euphorbia hirta using in vivo Rodent Micronucleus Assay
نویسندگان
چکیده
منابع مشابه
Anticlastogenic Effect of Eryngium foetidum L. by Erythrocyte Micronucleus Assay
Spices and herbal vegetables have long been traditionally used in habitual diets in tropical regions including Thailand. They contain not only essential nutrients but also are rich in various phytochemicals such as polyphenols, terpenes, alkaloids and phenolic acids, etc. The purified or crude extracts from some plants have been demonstrated to play a vital role in prevention and treatment of s...
متن کاملGenotoxicity of Euphorbia hirta: an Allium cepa assay.
The potential genotoxic effects of methanolic extracts of Euphorbia hirta which is commonly used in traditional medicine to treat a variety of diseased conditions including asthma, coughs, diarrhea and dysentery was investigated using Allium cepa assay. The extracts of 125, 250, 500 and 1,000 µg/mL were tested on root meristems of A. cepa. Ethylmethanesulfonate was used as positive control and ...
متن کاملEvaluation of leishmanicidal effect of Euphorbia petiolata extract by in vivo anti-leishmanial assay using promastigotes of Leishmania major
Objective: The extract of different species of Euphorbia has been successfully used as a remedy for treatment of cutaneous leishmaniasis. The aim of this study was to assess the in vitro leishmanicidal effect of Euphorbia petiolata (E. petiolata) extract. Materials and Methods: Ethanolic percolated and methanolic Soxhlet extract of E. petiolata on promastigotes of L. major at different concentr...
متن کاملCytotoxicity and genotoxicity assessment of Euphorbia hirta in MCF-7 cell line model using comet assay.
OBJECTIVE To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay. METHODS The cytotoxicity of E. hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E. hirta was assessed by using Comet assay. RESULTS Both toxicity tests exhibited significant toxicity result. In the comet as...
متن کاملBRONCHODILATOR EFFECT OF ALCOHOLIC EXTRACT OF Euphorbia hirta linn
The bronchodilator effect of alcoholic extract of Euphorbia hirta Linn was evaluated at different doses (50,100 and 200mg/kg,p.o), using histamine aerosol test model. A dose dependent bronchodilator effect was observed in E. hirta pretreated animals. The extract of E. hirta at a dose of 200mg/kg was found to be more effective in histamine induced broncho constriction and a significant (p<0.001)...
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ژورنال
عنوان ژورنال: International Journal of Current Microbiology and Applied Sciences
سال: 2018
ISSN: 2319-7692,2319-7706
DOI: 10.20546/ijcmas.2018.706.444